ParkinsonCanadaV1, Main, Exploration, bibRecord, 000685

Improving outcomes of subthalamic nucleus deep brain stimulation in Parkinson's disease.

Identifieur interne : 000685 ( Main/Exploration ); précédent : 000684; suivant : 000686

Improving outcomes of subthalamic nucleus deep brain stimulation in Parkinson's disease.

Auteurs : Ausaf A. Bari [Canada] ; Alfonso Fasano [Canada] ; Renato P. Munhoz [Canada] ; Andres M. Lozano [Canada]

Source :

Expert review of neurotherapeutics [ 1744-8360 ] ; 2015.

RBID : pubmed:26377740

English descriptors

KwdEn :
- Deep Brain Stimulation (methods), Humans, Parkinson Disease (physiopathology), Parkinson Disease (therapy), Subthalamic Nucleus (physiology), Treatment Outcome.
MESH :
- methods : Deep Brain Stimulation.
- physiology : Subthalamic Nucleus.
- physiopathology : Parkinson Disease.
- therapy : Parkinson Disease.
- Humans, Treatment Outcome.

Abstract

The subthalamic nucleus (STN) has been a major target of deep brain stimulation (DBS) for Parkinson's disease (PD) over the past 20 years. The benefits of DBS of the STN include: decreased motor fluctuations and bradykinesia, tremor reduction and a reduction in dopaminergic drug requirements and dyskinesias. Despite these overall positive effects, the outcomes of STN DBS can be variable, contributing to the debate over the best DBS target for PD. Here, the authors review the current practice of STN DBS and also review both the existing and emerging technologies that are likely to improve the accuracy and effectiveness of STN DBS for PD. The authors emphasize patient selection, accuracy of electrode placement within the brain and the selection of appropriate stimulation parameters to optimize clinical benefits.

DOI: 10.1586/14737175.2015.1081815
PubMed: 26377740

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">The subthalamic nucleus (STN) has been a major target of deep brain stimulation (DBS) for Parkinson's disease (PD) over the past 20 years. The benefits of DBS of the STN include: decreased motor fluctuations and bradykinesia, tremor reduction and a reduction in dopaminergic drug requirements and dyskinesias. Despite these overall positive effects, the outcomes of STN DBS can be variable, contributing to the debate over the best DBS target for PD. Here, the authors review the current practice of STN DBS and also review both the existing and emerging technologies that are likely to improve the accuracy and effectiveness of STN DBS for PD. The authors emphasize patient selection, accuracy of electrode placement within the brain and the selection of appropriate stimulation parameters to optimize clinical benefits.</div>
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La maladie de Parkinson au Canada (serveur d'exploration)

Improving outcomes of subthalamic nucleus deep brain stimulation in Parkinson's disease.

Improving outcomes of subthalamic nucleus deep brain stimulation in Parkinson's disease.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson au Canada (serveur d'exploration)
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